OUR PUBLICATIONS

  • López MG, Chiner-Oms Á, García de Viedma D, Ruiz-Rodriguez P, Bracho MA, Cancino-Muñoz I, D’Auria G, de Marco G, García-González N, Goig GA, Gómez-Navarro I, Jiménez-Serrano S, Martinez-Priego L, Ruiz-Hueso P, Ruiz-Roldán L, Torres-Puente M, Alberola J, Albert E, Aranzamendi Zaldumbide M, Bea-Escudero MP, Boga JA, Bordoy AE, Canut-Blasco A, Carvajal A, Cilla Eguiluz G, Cordón Rodríguez ML, Costa-Alcalde JJ, de Toro M, de Toro Peinado I, del Pozo JL, Duchêne S, Fernández-Pinero J, Fuster Escrivá B, Gimeno Cardona C, González Galán V, Gonzalo Jiménez N, Hernáez Crespo S, Herranz M, Lepe JA, López-Causapé C, López-Hontangas JL, Martín V, Martró E, Milagro Beamonte A, Montes Ros M, Moreno-Muñoz R, Navarro D, Navarro-Marí JM, Not A, Oliver A, Palop-Borrás B, Parra Grande M, Pedrosa-Corral I, Pérez González MC, Pérez-Lago L, Pérez-Ruiz M, Piñeiro Vázquez L, Rabella N, Rezusta A, Robles Fonseca L, Rodríguez-Villodres A, Sanbonmatsu-Gámez S, Sicilia J, Soriano A, Tirado Balaguer MD, Torres I, Tristancho A, Marimón JM, SeqCOVID-Spain consortium, Coscolla M, González-Candelas F, Comas I. The first wave of the COVID-19 epidemic in Spain was associated with early introductions and fast spread of a dominating genetic variant. Nat Genet. 2021. https://doi.org/10.1038/s41588-021-00936-6
  • Moreno-Molina M, Shubladze N, Khurtsilava I, Avaliani Z, Bablishvili N, Torres-Puente M, Villamayor L, Gabrielian A, Rosenthal A, Vilaplana C, Gagneux S, Kempker RR, Vashakidze S, Comas I. Genomic analyses of Mycobacterium tuberculosis from human lung resections reveal a high frequency of polyclonal infections. Nat Comm. 2021, 12 (1): 2716.
  • López MG, Fass M, Rivas JG, Carbonell-Caballero J, Vera P, Puebla A, Defacio R, Dopazo J, Paniego N, Hopp HE, Lia VV. Plastome genomics in South American maize landraces: chloroplast lineages parallel the geographic structuring of nuclear gene pools. Ann Bot. 2021 March 07;mcab038.
  • Goig GA, Cancino-Muñoz I, Torres-Puente M, Villamayor LM, Navarro D, Borrás R, Comas I. Whole-genome sequencing of Mycobacterium tuberculosis directly from clinical samples for high-resolution genomic epidemiology and drug resistance surveillance: an observational study. The Lancet Microbe. 2020 August 01; 1 (4): E175-E183. https://doi.org/10.1016/S2666-5247(20)30060-4
  • Goig GA, Blanco S, García-Basteiro AL, Comas I. Contaminant DNA in bacterial sequencing experiments is a major source of false genetic variability. BMC Biol. 2020 March 02; 18: 24. https://doi.org/10.1186/s12915-020-0748-z
  • Comas I, Cancino-Muñoz I, Mariner-Llicer C, Goig GA, Ruiz-Hueso P, Francés- Cuesta C, García-González N, González-Candelas F. Use of next generation sequencing technologies for the diagnosis and epidemiology of infectious diseases. Enferm Infecc Microbiol Clin. 2020 Jan;38 Suppl 1:32-38. English, Spanish.
  • López MG, Dogba JB , Torres-Puente M, Goig GA, Moreno-Molina M, Villamayor LM, Cadmus S, Comas I. Tuberculosis in Liberia: high multidrug-resistance burden, transmission and diversity modelled by multiple importation events. Microb Genom. 2020 Jan 14; DOI: 10.1099/mgen.0.000325
  • Xu Y, Cancino-Muñoz I, Torres-Puente M, Villamayor LM, Borrás R, Borrás-Máñez M, Bosque M, Camarena JJ, Colomer-Roig E, Colomina J, Escribano I, Esparcia-Rodríguez O, Gil-Brusola A, Gimeno C, Gimeno-Gascón A, Gomila-Sard B, González-Granda D, Gonzalo-Jiménez N, Guna-Serrano MR, López-Hontangas JL, Martín-González C, Moreno-Muñoz R, Navarro D, Navarro M, Orta N, Pérez E, Prat, Carlos Rodríguez J, Ruiz-García MM, Vanaclocha H, Colijn C, Comas I. High-resolution mapping of tuberculosis transmission: Whole genome sequencing and phylogenetic modelling of a cohort from Valencia Region, Spain. PLoS Med. 2019 Oct 31; 16 (10): e1002961.
  • Cancino-Muñoz I, Gil-Brusola A, Torres-Puente M, Mariner-Llicer C, Dogba J, Akinseye V, Adesokan K, Kwaghe A, Ejeh F, Cadmus S, Comas I. Development and application of affordable SNP typing approaches to genotype Mycobacterium tuberculosis complex strains in low and high burden countries. Sci Rep. 2019 Oct 25; 9: 15343.
  • Goig GA, Torres-Puente M, Mariner-Llicer C, Villamayor LM, Chiner-Oms Á, Gil-Brusola A, Borrás R, Comas I. Towards next-generation diagnostics for tuberculosis: identification of novel molecular targets by large-scale comparative genomics. Bioinformatics. 2019 Oct 3; btz729
  • Chiner-Oms Á, Berney M, Boinett C, González-Candelas F, Young DB, Gagneux S, Jacobs WR, Parkhill J, Cortes T, Comas I. Genome-wide mutational biases fuel transcriptional diversity in the Mycobacterium tuberculosis complex. Nat Comm. 2019; 10 (1): 3994.
  • Meehan CJ, Goig GA, Kohl TA, Verboven L, Dippenaar A, Ezewudo M, Farhat MR, Guthrie JL, Laukens K, Miotto P, Ofori-Anyinam B, Dreyer V, Supply P, Suresh A, Utpatel C, van Soolingen D, Zhou Y, Ashton PM, Brites D, Cabibbe AM, de Jong BC, de Vos M, Menardo F, Gagneux S, Gao Q, Heupink TH, Liu Q, Loiseau C, Rigouts L, Rodwell TC, Tagliani E, Walker TM, Warren RM, Zhao Y, Zignol M, Schito M, Gardy J, Cirillo DM, Niemann S, Comas I, Van Rie A. Whole genome sequencing of Mycobacterium tuberculosis: current standards and open issues. Nat Rev Microb. 2019; 17: 533 – 545
  • Chiner-Oms Á, Comas I. Large genomics datasets shed light on the evolution of the Mycobacterium tuberculosis complex. Infect Genet Evol. 2019; 72:10-15.
  • Chiner-Oms Á, Sánchez-Busó L., Corander J, Gagneux S, Harris S, Young D, González-Candelas F., Comas I. Genomic determinants of speciation and spread of the Mycobacterium tuberculosis complex. Sci Adv. 2019;5(6):eaaw3307
  • Cancino-Muñoz I, Moreno-Molina M, Furió V, Goig GA, Torres-Puente M, Chiner-Oms Á, et al. Cryptic Resistance Mutations Associated With Misdiagnoses of Multidrug-Resistant Tuberculosis. J Infect Dis. 2019 Jun 19;220(2):316–20
  • Moreno-Molina M, Comas I, Furió V. The Future of TB Resistance Diagnosis: The Essentials on Whole Genome Sequencing and Rapid Testing Methods. Arch Bronconeumol. 2019 Feb 19.
  • Chiner-Oms Á, González-Candelas F, Comas I. Gene expression models based on a reference laboratory strain are poor predictors of Mycobacterium tuberculosis complex transcriptional diversity. Sci Rep. 2018 Feb 28;8(1):3813.
  • Comas I, Gardy J. TB transmission: closing the gaps. EBioMedicine. 2018; 34:4 – 5
  • Comas I, Hailu E, Kiros T, Bekele S, Mekonnen W, Gumi B, Tschopp R, Ameni G, Hewinson RG, Robertson BD, Goig GA, Stucki D, Gagneux S, Aseffa A, Young D, Berg S. Population genomics of Mycobacterium tuberculosis in Ethiopia contradicts the virgin soil hypothesis for human tuberculosis in Sub-Saharan Africa. Curr Biol. 2015 Dec 21;25(24):3260-6.
  • Comas I, Coscolla M, Luo T, Borrell S, Holt K, Kato-Maeda M, Parkhill J, Malla B, Berg S, Thwaites G, Yeboah-Manu D, Bothamley G, Mei J, Wei L, Bentley S, Harris S, Niemann S, Diel R, Aseffa A, Gao Q, Young D, Gagneux S. Out-of-Africa migration and Neolithic coexpansion of Mycobacterium tuberculosis with modern humans. Nat Genet. 2013; 45(10):1176-1182.
  • Comas I, Borrell S, Roetzer A, Rose G, Malla B, Kato-Maeda M, Galagan J, Niemann S, Gagneux S. Whole-genome sequencing of rifampicin-resistant Mycobacterium tuberculosis strains identifies compensatory mutations in RNA polymerase genes. Nat Genet. 2011 Dec 18;44(1):106-10.
  • Comas I, Chakravartti J, Small P, Galagan J, Niemann S, Kremer K, Ernst J, Gagneux S. Human T cell epitopes of Mycobacterium tuberculosis are evolutionarily hyperconserved. Nat Genet. 2010; 42(6):498-503.
  • Comas I, Gagneux S. The past and future of tuberculosis research. PLoS Pathog. 2009 Oct;5(10):e1000600.

COLLABORATIONS

  • Pérez Lago L, Pérez Latorre L, Herranz M, Tejerina F, Sola-Campoy PJ, Sicilia J, Suárez-González J, Andrés-Zayas C, Chiner-Oms A, Jiménez-Serrano S, García-González N, Comas I, González-Candelas F, Martínez-Laperche C, Catalán P, Muñoz P, García de Viedma D, Gregorio Marañón Microbiology-ID COVID 19 Study Group. Complete analysis of the epidemiological scenario around a SARS-CoV-2 reinfection: previous infection events and subsequent transmission. mSphere. 2021 Sep 8;e0059621. Online ahead of print.
  • Pérez-Lago L, Aldámiz-Echevarría T, García-Martínez R, Pérez-Latorre L, Herranz M, Sola-Campoy PJ, Suárez-González J, Martínez-Laperche C, Comas I, González-Candelas F, Catalán P, Muñoz P, García de Viedma D. Different within-host viral evolution dynamics in severely immunosuppressed cases with persistent SARS-CoV-2. Biomedicines. 2021; 9 (7): 808
  • Rocha DMGC, Magalhães C, Cá B, Ramos A, Carvalho T, Comas I, Guimarães JT, Novais Bastos H, Saraiva M, Osório NS. Heterogeneous streptomycin resistance level among Mycobacterium tuberculosis strains from the same transmission cluster. Frontiers in Microbiology. 2021; 12: 1380
  • Pérez-Lago L, Martínez Lozano H, Pajares Díaz JA, Díaz Gómez A, Machado M, Sola-Campoy PJ, Herranz M, Buenestado-Serrano S, Valerio M, Olmedo M, Andrés Zayas C, Comas I, González-Candelas F, Bañares R, Catalán P, Muñoz P, García de Viedma D, Gregorio Marañón Microbiology-ID COVID. Proper assignation of reactivation in a COVID-19 recurrence initially interpreted as a reinfection. J Infect Dis. 2021; 224 (5): 788-792
  • Ticlla MR, Hella J, Hiza H, Sasamalo M, Mhimbira F, Rutaihwa LK, Droz S, Schaller S, Reither K, Hilty M, Comas I, Beisel C, Schmid CD, Fenner L, Gagneux S. The sputum microbiome in pulmonary tuberculosis and its association with disease manifestations: a cross-sectional study. Frontiers in Microbiology. 2021; 12: 2175
  • Menardo F, Rutaihwa LK, Zwyer M, Borrell S, Comas I, Costa Conceição E, Coscolla M, Cox H, Joloba M, Dou HY, Feldmann J, Fenner L, Fyfe J, Gao Q, García de Viedma D, Garcia-Basteiro AL, Gygli SM, Hella J, Hiza H, Jugheli L, Kamwela L, Kato-Maeda M, Liu Q, Ley SD, Loiseau C, Mahasirimongkol S, Malla B, Palittapongarnpim P, Rakotosamimanana N, Rasolofo V, Reinhard M, Reither K, Sasamalo M, Silva Duarte R, Sola C, Suffys P, Batista Lima KV, Yeboah-Manu D, Beisel C, Brites D, Gagneux S. Local adaptation in populations of Mycobacterium tuberculosis endemic to the Indian Ocean Rim. F1000Research. 2021; 10: 60
  • Hodcroft EB, Zuber M, Nadeau S, Vaughan TG, Crawford KHD, Althaus CL, Reichmuth ML, Bowen JE, Walls AC, Corti D, Bloom JD, Veesler D, Mateo D, Hernando A, Comas I, González Candelas F, SeqCOVID-SPAIN consortium, Stadler T, Neher RA. Spread of a SARS-CoV-2 variant through Europe in the summer of 2020. Nature. 2021; 595: 707-712
  • Martínez-Lirola M, Jajou R, Mathys V, Martin A, Cabibbe AM, Valera A, Sola-Campoy PJ, Abascal E, Rodríguez-Maus S, Garrido-Cárdenas JA, Bonillo M, Chiner-Oms Á, López B, Vallejo-Godoy S, Comas I, Muñoz P, Cirilo DM, Soolingen D, Pérez-Lago L, García de Viedma DG. Integrative transnational analysis to dissect tuberculosis transmission events along the migratory route from Africa to Europe. J Travel Med. 2021 Apr 5:taab054. doi: 10.1093/jtm/taab054.
  • Pérez-Lago L, Sola Campoy PJ, Buenestado-Serrano S, Catalán P, Estévez A, de la Cueva VM, López MG, Herranz M, Suárez-González J, Alcalá L, Comas I, González-Candelas F, Muñoz P, García de Viedma D. Epidemiological, clinical and genomic snapshot of the first 100 B.1.1.7 SARS-CoV-2 cases in Madrid. J Travel Med. 2021 Mar 24; taab044, doi: https://doi.org/10.1093/jtm/taab044
  • Van Rie A, Garcia de Viedma D, Meehan C, Comas I, Heupink TH, De Vos E, de Oñate WA, Mathys V, Ceyssens P-J, Groenen G, González‐Candelas F, Forier A, Juengst E. Whole-genome sequencing for TB source investigations: principles of ethical precision public health. Int J Tuberc Lung Dis. 2021 Mar 1; 25(3): 222-227.
  • Jbara S, Herranz M, Sola-Campoy PJ, Rodríguez-Grande C, Chiner-Oms Á, Comas I, Muñoz P, García de Viedma D, Pérez-Lago L. Overlapping prison/community tuberculosis outbreaks in Costa Rica revealed by alternative analysis of suboptimal material. Transbound Emerg Dis. 2021 Mar 9. doi: 10.1111/tbed.14063
  • Jiménez-Ruano AC, Madrazo-Moya CF, Cancino-Muñoz I, Mejía-Ponce PM, Licona-Cassani C, Comas I, Muñiz-Salazar R, Zenteno-Cuevas R. Whole genomic sequencing based genotyping reveals a specific X3 sublineage restricted to Mexico and related with multidrug resistance. Sci Rep. 2021 Jan 03; 11: 1870
  • Pérez‐Lago L, Monteserin J, Paul R, Maus SR, Yokobori N, Herranz M, Sicilia J, Acosta F, Fajardo S, Chiner‐Oms Á, Matteo M, Simboli N, Comas I, Muñoz P, López B, Ritacco V, García de Viedma D. Recurrences of multidrug‐resistant tuberculosis: strains involved, within‐host diversity, and fine‐tuned allocation of reinfections. Transbound Emerg Dis. 2021;00:1–10.
  • Alm E, Broberg EK, Connor T, Hodcroft EB, Komissarov AB, Maurer-Stroh S, Melidou A, Neher RA, O’Toole A, Pereyaslov D, The WHO European Region sequencing laboratories and GISAID EpiCoV group. Geographical and temporal distribution of SARS-CoV-2 clades in the WHO European Region, January to June 2020. Euro Surveill. 2020;25(32):pii=2001410.
  • Sevilla LM, Bigas J, Chiner-Oms Á, Comas I, Sentandreu V, Pérez P. Glucocorticoid-dependent transcription in skin requires epidermal expression of the glucocorticoid receptor and is modulated by the mineralocorticoid receptor. Sci Rep. 2020 Nov 03; 10(1): 18954.
  • Wilson DJ, CRyPTIC Consortium. GenomegaMap: Within-Species Genome-Wide dN/dS Estimation from over 10,000 Genomes. Mol Biol Evol. 2020 Aug 1;37(8):2450-2460.
  • Liu Q, Wei J, Li Y, Wang M, Su J, Lu Y, López MG, Qian X, Zhu Z, Wang H, Gan M, Jiang Q, Fu Y, Takiff HE, Comas I, Li F, Lu X, Fortune SM, Gao Q. Mycobacterium tuberculosis clinical isolates carry mutational signatures of host immune environments. Sci Adv. 2020 May 29; 6 (22): aba4901 .
  • Sousa J, Cá B, Maceiras AR, Simões-Costa L, Fonseca KL, Fernandes AI, Ramos A, Carvalho T, Barros L, Magalhães C, Chiner-Oms Á, Machado H, Veiga MI, Singh A, Pereira R, Amorim A, Vieira J, Vieira CP, Bhatt A, Rodrigues F, Rodrigues PNS, Gagneux S, Castro AG, Guimarães JT, Bastos HN, Osório NS, Comas I, Saraiva M. Mycobacterium tuberculosis associated with severe tuberculosis evades cytosolic surveillance systems and modulates IL-1β production. Nat Comm. 2020; 11 (1): 1949.
  • Abascal E, Herranz M, Acosta F, Agapito J, Cabibbe AM, Monteserin J, Ruiz Serrano MJ, Gijón P, Fernández-González F, Lozano N, Chiner-Oms Á, Cáceres T, Gómez Pintado P, Acín E, Valencia E, Muñoz P, Comas I, Cirillo DM, Ritacco V, Gotuzzo E, García de Viedma D. Screening of inmates transferred to Spain reveals a peruvian prison as a reservoir of persistent Mycobacterium tuberculosis MDR strains and mixed infections. Sci Rep. 2020 Feb 17; 10 (1): 2704.
  • Castañeda-García A, Martín-Blecua I, Cebrian-Sastre E, Chiner-Oms Á, Torres-Puente M, Comas I, Blázquez J. Specificity and mutagenesis bias of the mycobacterial alternative mismatch repair analyzed by mutation accumulation studies. Sci Adv. 2020 Feb 12; 6 (7): eaay4453
  • Zenteno-Cuevas R, Fernandez E, Viveros D, Madrazo-Moya CF, Cancino-Muñoz I, Comas I, Gonzalez-Covarrubias V, Barbosa-Amezcua M, Cuevas-Cordoba B. Characterization of polymorphisms associated with multidrug-resistant tuberculosis by whole genomic sequencing: a preliminary report from Mexico. Microb Drug Resist. 2019 Dec 23; Ahead of print, http://doi.org/10.1089/mdr.2019.0054
  • Arias L, Goig GA, Cardona P, Torres-Puente M, Díaz J, Rosales Y, Garcia Aguilera E, Tapia G, Comas I, Vilaplana C, Cardona PJ. Influence of gut microbiota on progression to tuberculosis generated by high fat diet-induced obesity in C3HeB/FeJ mice. Front Immunol. 2019 Oct 18; 10: 2464
  • Gomez-Valero L, Chiner-Oms Á, Comas I, Buchrieser C. Evolutionary dissection of the Dot/Icm system based on comparative genomics of 58 Legionella species. Genome Biol Evol. 2019; 11 (9): 2619 – 2632.
  • Madrazo-Moya CF, Cancino-Muñoz I, Cuevas-Córdoba B, González-Covarrubias V, Barbosa-Amezcua M, et al. Whole genomic sequencing as a tool for diagnosis of drug and multidrug-resistance tuberculosis in an endemic region in Mexico. PLOS ONE. 2019 14(6): e0213046
  • Domínguez J, Acosta F, Pérez-Lago L, Sambrano D, Batista V, De La Guardia C, Abascal E, Chiner-Oms Á, Comas I, González P, Bravo J, Del Cid P, Rosas S, Muñoz P, Goodridge A, García de Viedma D. Simplified model to survey tuberculosis transmission in countries without systematic molecular epidemiology programs. Emerg Infect Dis. 2019;25 (3):507
  • Liu Q, Ma A, Wei L, Pang Y, Wu B, Luo T, Zhou Y, Zheng HX, Jiang Q, Gan M, Zuo T, Liu M, Yang C, Jin L, Comas I, Gagneux S, Zhao Y, Pepperell CS, Gao Q.China’s tuberculosis epidemic stems from historical expansion of four strains of Mycobacterium tuberculosis. Nat Ecol Evol 2018; 2 (12): 1982 – 1992.
  • Herranz M, Pole I, Ozere I, Chiner-Oms Á, Martínez-Lirola M, Pérez-García F, Gijón P, Ruiz MJ, Clotet L, Cuevas O, Comas I, Bouza E, Perez-Lago L, García-de-Viedma D. Mycobacterium tuberculosis acquires limited genetic diversity in prolonged infections, reactivations and transmissions involving multiple hosts. Front Microbiol. 2018;8:2661
  • Abascal E, Pérez-Lago L, Martínez-Lirola M, Chiner-Oms Á, Herranz M, Chaoui I, Comas I, El Messaoudi MD, Garrido Cárdenas JA, Santantón S, Bouza E, García-de-Viedma D. Whole-genome sequencing–based analysis of tuberculosis in migrants: rapid tools for cross-border surveillance and to distinguish between recent transmission in the host country and new importations. Euro Surveill. 2018; 24(4):1800005
  • Castaño Aroca MJ, Calabuig Muñoz E, Comas I, Gil-Brusola A. Tuberculosis of the elbow: A rare form of presentation of extrapulmonary tuberculosis. Enferm Infecc Microbiol Clin. 2018 Sept 18; 31(8): 550-551.
  • The CRyPTIC Consortium and the 100,000 Genomes Project. Prediction of Susceptibility to First-Line Tuberculosis Drugs by DNA Sequencing. N Engl J Med. 2018 Oct 11;379(15):1403–15
  • Castejon M, Menéndez MC, Comas I, Vicente A, Garcia MJ. Whole-genome sequence analysis of the Mycobacterium avium complex and proposal of the transfer of Mycobacterium yongonense to Mycobacterium intracellulare subsp. yongonense subsp. nov. Int J Syst Evol Micr. 2018 Apr 23; 38 (6): 1998-2005.
  • Novais Bastos H, Osório NS, Gagneux S, Comas I, Saraiva M. The Troika host–pathogen–extrinsic factors in tuberculosis: modulating inflammation and clinical outcomes. Front Immunol. 2018 Jan 1; 8: 1948
  • Ezewudo M, Borens A, Chiner-Oms Á, Miotto P, Chindelevitch L, Starks A, Hanna D, Liwski R, Zignol M, Gilpin C, Niemann S, Kohl TA, Warren R, Crook D, Gagneux S, Hoffner S, Rodrigues C, Comas I, Engelthaler D, Alland D, Rigouts L, Lange C, Dheda K, Hasan R, McNerney R, Cirillo DM, Schito M, Rodwell T. Integrating standardized whole genome sequence analysis with a global Mycobacterium tuberculosis antibiotic resistance knowledgebase. Sci Rep. 2018; 8(1):15382
  • Luo T, Comas I, Luo D, Lu B, Wu J, Wei L, Yang C, Liu Q, Gan M, Sun G, Shen X, Liu F, Gagneux S, Mei J, Lan R, Wan K, Gao Q. Southern East Asian origin and coexpansion of Mycobacterium tuberculosis Beijing family with Han Chinese. Proc Natl Acad Sci U S A. 2015 Jun 30;112(26):8136-41.
  • Bos KI, Harkins KM, Herbig A, Coscolla M, Weber N, Comas I, Forrest SA, Bryant JM, Harris SR, Schuenemann VJ, Campbell TJ, Majander K, Wilbur AK, Guichon RA, Wolfe Steadman DL, Cook DC, Niemann S, Behr MA, Zumarraga M, Bastida R, Huson D, Nieselt K, Young D, Parkhill J, Buikstra JE, Gagneux S, Stone AC, Krause J. Pre-Columbian mycobacterial genomes reveal seals as a source of New World human tuberculosis. Nature. 2014 Oct 23;514(7523):494-7.
  • Sánchez-Busó L, Comas I, Jorques G, González-Candelas F. Recombination drives genome evolution in outbreak-related Legionella pneumophila isolates. Nat Genet. 2014 Nov;46(11):1205-11.
  • Pérez-Lago L, Comas I, Navarro Y, González-Candelas F, Herranz M, Bouza E, García-de-Viedma D. Whole genome sequencing analysis of intrapatient microevolution in Mycobacterium tuberculosis: potential impact on the inference of tuberculosis transmission. J Infect Dis. 2014 Jan 1;209(1):98-108.

Books / Book chapters

  • López MG. “19. Genómica y Postgenómica”. Pages 300-328 from the book “Genética: una guía de problemas y de cómo resolverlos“. ISBN 978-620-0-01540-2. 2019 June 11. Editorial Academica Espanola
  • Comas I, Chiner-Oms A. Actuaciones sobre la enfermedad y conexión con la clínica”. Pages 35-71 from the book “Una visión global de la pandemia COVID-19: qué sabemos y qué estamos investigando desde el CSIC“. ISBN: 978-84-00-10779-6. 2021 March 29. Editorial CSIC.

THESIS

  • Decoding tuberculosis transmission and drug resistance in Valencia region using whole genome sequencing.
    • Author: Irving Cancino Muñoz
    • Supervision: Iñaki Comas
    • Program: Doctoral Program in Biomedicine and Biotechnology (University of Valencia)
    • Date: 26/10/2020
  • Applied genomics for tuberculosis diagnosis and surveillance.
    • Author: Galo Adrian Goig
    • Supervision: Iñaki Comas
    • Program: Doctoral Program in Biomedicine and Biotechnology (University of Valencia)
    • Date: 24/07/2020
  • Evolutionary systems biology of the Mycobacterium tuberculosis complex.
    • Author: Álvaro Chiner-Oms
    • Supervision: Iñaki Comas and Fernando González-Candelas
    • Program: Doctoral Program in Biomedicine and Biotechnology (University of Valencia)
    • Date: 28/06/2019
  • Caracterización epidemiológica, clínica, microbiológica y genómica de Mycobacterium tuberculosis en el departamento de salud La Fe de Valencia.
    • Author: Ana Gil Brusola
    • Supervision: Jose Miguel Nogueira Coito and Iñaki Comas.
    • Program: Doctoral Program in Medicine (University of Valencia)
    • Date: 06/03/2018
  • Evolución de la tuberculosis en Castellón. Caracterización genotípica mediante 15 MIRU-VNTR.
    • Author: Barbara Gomila Sard
    • Supervision: Fernando González – Candelas, Iñaki Comas and Rosario Moreno-Muñoz
    • Program: Doctoral Program in Microbiology (University of Valencia)
    • Date: 29/01/2016